CHOP is an abbreviated name for a combination of drugs used in chemotherapy for some common types of aggressive Non-Hodgkin Lymphoma (NHL). It consists of four drugs - Cyclophosphamide (also called Cytoxan/Neosar), Doxorubicin (or Adriamycin), Vincristine (Oncovin) and Prednisolone.
The first three drugs of the CHOP chemotherapy regimen are usually given as injections or infusions in veins on a single day, while prednisolone is taken as pills for five days.Each cycle is repeated every 3 weeks for 6-8 cycles.
CHOP chemotherapy is used for many of the common types of aggressive Non-Hodgkin Lymphomas including Diffuse Large B-Cell Lymphoma (DLBCL).
Its is also often combined with Rituximab in the R-CHOP regimen.