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CHOP

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Updated January 21, 2007

Definition:

CHOP is an abbreviated name for a combination of drugs used in chemotherapy for some common types of aggressive Non-Hodgkin Lymphoma (NHL). It consists of four drugs - Cyclophosphamide (also called Cytoxan/Neosar), Doxorubicin (or Adriamycin), Vincristine (Oncovin) and Prednisolone.

The first three drugs of the CHOP chemotherapy regimen are usually given as injections or infusions in veins on a single day, while prednisolone is taken as pills for five days.Each cycle is repeated every 3 weeks for 6-8 cycles.

CHOP chemotherapy is used for many of the common types of aggressive Non-Hodgkin Lymphomas including Diffuse Large B-Cell Lymphoma (DLBCL).

Its is also often combined with Rituximab in the R-CHOP regimen.

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