Blood-forming stem cells follow one of two different development pathways, or cell lines -- the lymphoid or the myeloid.
The myeloid cell line begins with a myeloblast. As the myeloblasts reproduce and become more specialized or mature, they will eventually develop into functional blood cells, including:
- Neutrophils
- Monocytes
- Eosinophils
- Basophils
- Macrophages
- Megakaryocytes
- Erythrocytes
It is the myeloid cell line that is affected in cancers such as acute myelogenous leukemia (AML) and chronic myelogenous leukemia (CML). Cells of the myeloid line make up about 85% of marrow cells.
Source:
Williams, L. "Comprehensive Review of Hematopoiesis and Immunology: Implications for Hematopoietic Stem Cell Transplant Recipients" in Ezzone, S. (2004) Hematopoietic Stem Cell Transplantation: A Manual for Nursing Practice Oncology Nursing Society: Pittsburgh, PA (pp.1- 12)
