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The Leukemia and Lymphoma Glossary

A glossary of terms commonly encountered during your journey with lymphoma or leukemia, explained in simple language.

Absolute Neutrophil Count (ANC)
A description of Absolute Neutrophil Count or ANC encountered during chemotherapy or sradiotherapy for lymphomas.

ABVD
Chemotherapy protocol for Hodgkin Lymphoma

Adjuvant Treatment
Some treatments like radiation or chemotherapy are often called adjuvant treatments. What does adjuvant therapy mean?

Adriamycin (Doxorubicin)
Adriamycin (also called Doxorubicin) is a drug used in cancer treatment.

Allogeneic
Allogeneic refers to a type of stem cell transplant. Learn about allogeneic stem cell transplant and how it works.

Alopecia
A definition or meaning of alopecia or hair loss during treatments like cheotherapy

Analgesic
Analgesics are used for pain control

Anemia
What is anemia? Definition of anemia.

Anemia
Learn what anemia is and how it affects the body.

Antibiotic
Antibiotics are used to control infections. Find out what antibiotics are.

Antiemetic
A definition of antiemetics

Apheresis
What does apheresis mean? What is plasma apheresis used for?

Apoptosis
The definition of apoptosis or programmed cell death

Autologous
Autologous refers to a type of stem cell transplant. Learn what autologous means, and how these types of transplants work.

Axillary Lymph Nodes
What are axillary lymph nodes? How are axillary nodes affected in Lymphoma?

B-cells
A B-cell is a type of blood cell that protects the body from infection. Find out more about B-cells.

B Lymphocyte
Learn about the function of infection fighting B lymphocytes.

Bence Jones Proteins
Learn what Bence Jones proteins are and where they got their name.

Biological Therapy
What is biological therapy? What are the agents used in biological therapy for lymphoma?

Biopsy
What does a biosy mean? what are the different ypes of biopsies? Why is it required?

Blast Cells
Learn what is meant by "blast cells" and what their significance is in blood cancers.

Blood Count
What is a blood count? Why do doctors order a blood count?

Bone Marrow
The bone marrow is that part of bone where blood cells are produced. Find out more about the bone marrow.

What is Bone Marrow Aspiration and Biopsy?
Bone marrow testing, or aspiration and biopsy, gives doctors an opportunity to see exactly what is going on with the cells in your marrow. Learn what bone marrow aspiration and biopsy is, and what to expect during the procedure.

Bone Marrow Transplants (BMT)
An introduction to bone marrow transplants (BMT). What are the types of bone marrow transplants?

Carcinogen
A carcinogen causes cancer. Find out what a carcinogen is.

Cause-Specific Survival (CSS)
Cause-specific survival (CSS) is a term used to describe survival in those sufferin from cancer. What does cause-specific survival mean?

CD20
CD20 is probably the most popular CD marker in lymphomas. Find out what CD20 really is.

Cell
What is a cell? Which cell is affected in lymphomas?

Cervical Lymph Nodes
What are cervical lymph nodes? How are cervical nodes affected in lymphoma?

Chemotherapy
What is chemotherapy? Why is it given?

CHOP
What is CHOP chemotherapy used in Non-Hodgkin Lymphomas? What are the drugs used in CHOP chemotherapy?

Chromosome Translocation
Certain changes to chromosomes, or mutations, can cause a healthy gene to become a cancer-causing gene. One of these types of changes is called a...

Colony-Stimulating Factor (CSF)
A definition of colony-stimulating factor or growth factors that help raise your blood counts to normal.

What is Combination Chemotherapy?
Learn about combination chemotherapy, and the principles it is based upon.

Complete Blood Count (CBC)
A complete blood count (CBC) is a commonly performed blood test. Find out what a complete blood count involves.

Complete Response (CR)
What do doctors mean by complete response (CR) after treatment? Is complete response (CR) the same as cure?

Cytopathology
Understand what a cytopathology report tells you.

Cytotoxic
What does cytotoxic mean? What are the types cytotoxic treatment?

What Does Differentiation Mean?
Find out the meaning of differentiation, and how it impacts cancer cells.

Disease Free Survival (DFS)
Disease-free survival (DFS) is a very commonly used term used to describe the results of cancer treatments. What does does disease free survival mean?

What is Engraftment?
Engraftment occurs when transplanted stem cells resume production of healthy blood cells in the recipients marrow. Learn how this occurs, and how we know its happening.

Event-Free Survival (EFS)
Event-free survival (EFS) is a term that is sometimes used in reports of therapies related to cancer treatment. What does event-free survival mean?

Extranodal
Find out the meaning of extranodal,and the difference between primary and secondary extranodal lymphoma.

Fine Needle Aspiration Cytology (FNAC)
What is an FNAC? When is fine needle aspiration cytology used in lymphomas?

First Line Therapy
Learn what is meant by first line therapy, and how it is used in the treatment of leukemia and lymphoma.

What is Hematopoiesis
Hematopoiesis is the process of production, multiplication, and specialization of blood cells in the bone marrow.

Hematuria
Blood in the urine can cause a good deal of anxiety! Learn about what hematuria is, and what causes it in leukemia and lymphoma patients.

Histopathology
Understand what your histopathology report is all about.

Immunoglobulin
Immunoglobulins are an important part of the immune system. Learn about how they are made, and how they are named.

Hyperpigmentation
Hyperpigmentation, or darkening of the skin, is a common side effect of both radiation therapy and chemotherapy. Learn about the meaning of hyperpigmentation.

HTLV- Human T cell Lymphotropic Virus
A description of HTLV-Human T cell Lymphotropic Virus.

Immunohistochemistry (IHC)
Immunohistochemistry is a special technique used in labs to test cells. Find out more about immunohistochemistry in medical practice.

What is a Lumbar Puncture?
A lumbar puncture, or spinal tap, helps doctors determine if abnormal cells are present in the fluid around your spine. Learn about why this procedure is done, and what to expect if you need one.

Lymph
Learn about this important part of our immune system

Lymphadenopathy
Lymphadenopathy refers to disease or enlargement of lymph nodes. Find out more about lymphadenopathy.

What is LymphoCide (Epratuzumab)?
LymphoCide (Epratuzumab) is a monoclonal antibody that is under investigation for the treatment of lymphomas.

Lymphocyte
Lymphocytes are a type of white blood cell. Learn the full definition.

Lymphoid Cell Line
What is the lymphoid cell line? Where do B Cells and T cells come from? Find out here!

M- Protein
In myeloma, there is over-production of a single type of immunoglobulin protein, called the M- protein. Learn about what the M- protein is and where it comes from.

Malignancy
Malignancy is a term used to describe cancer. Understand what malignancy really means.

Mantle Field Radiation
Mantle field radiation is a type of extended field radiation used to treat Hodgkin's lymphoma.

Median Survival (MS)
Median survival is a term that indicates how long an individual may survive with a cancer and its treatment. Find out wha median survival means.

Mediastinal Lymph Nodes
What are mediastinal lymph nodes? How are mediatinal lymph nodes affected in lymphoma?

MGUS: Monoclonal Gammopathy of Undetermined Significance
Learn what MGUS is and how it is different from myeloma.

Monoclonal Antibody
A definition of antibody as relevant in lymphomas.

What Are Monocytes?
Learn about what monocytes are, and the role they play in the immune system.

Mucositis
The meaning of mucositis as encountered during chemotherapy or radiotherapy for cancers like lymphomas.

Myeloid Cell Line
What is the myeloid cell line? Find out here.

Natural Killer Cell
Learn about the role of natural killer cells in our immunity.

Neutropenia
Learn what neutropenia is and how it affects the body.

Osteolytic Lesions
Osteolytic lesions are characteristic areas of damage caused by myeloma. Learn about osteolytic lesions and how they are formed.

Overall Survival (OS)
Overall survival (OS) is a common term used to describe the chances of survival and cure in cancer. What does overall survival mean?

Pancytopenia
Learn what the term pancytopenia means.

Partial Response (PR)
What does partial response (PR) mean? What happens to patients after a partial response to cancer treatments?

Peripheral Blood Stem Cells (PBSC)
Peripheral blood stem cells are immature cells circulating in blood. Find out more about peripheral blood stem cells.

Peripheral Blood Stem Cell Transplants (PBSCT)
What is a peripheral blood stem cell transplant (PBSCT)? what are the types of stem cell transplantation?

What Are Plasma Cells?
Plasma cells play an important role in helping our bodies fight infection. Learn how they do this and what happens when they become cancerous.

What Are Plasma Cells?
Learn about plasma cells an the important role they play in our immune system.

What is a PICC Line?
An image of a peripherally inserted central catheter (PICC)

Plasmacytoma
Plasmacytoma is a mass of plasma cells in myeloma. Learn what plasmacytoma is and where it comes from.

Platelets
Learn what platelets are and how they function.

Polymorphonuclear leukocyte
Polymorphonuclear leukocytes are a type of white blood cell that helps the body fight off infection.

Progression Free Survival (PFS)
Progression-free survival (PFS) is a term that is used to describe treatment results. What does progression-free survival mean?

Progressive Disease (PD)
What does progressive disease (PD) mean? What happens to those with disease progression?

R-CHOP
What is R-CHOP chemotherapy used in Non-Hodgkin Lymphomas (NHL)? What are the drugs used in R-CHOP chemotherapy?

Radiotherapy
What is radiotherapy? Why is it given?

Reed Sternberg Cells
Find out what Reed Sternberg cells are

What is a Relapse?
Find out what is meant by a relapse of cancer.

Remission
An explanation of remission

Retroperitoneal Lymph Nodes
What are retroperitoneal lymph nodes? How are retroperitoneal lymph nodes affected in lymphoma?

What Is a Risk Factor?
A look at risk factors and the role they play in predicting if you will get cancer or not.

What is Second Line Therapy?
Learn about what is meant by second line therapy and when it is used in leukemia and lymphoma

What is Meant By Quality of Life?
Learn what is meant by the term Quality of Life, and how it impacts the decisions you make about your cancer care.

Spleen
Learn about the spleen and the role it plays in our lymphatic system.

Splenomegaly
Learn what splenomegaly means, as well as signs and symptoms of this condition.

Stable Disease (SD)
What does stable disease (SD) mean? What happens to patients with stable disease (SD) after reatment?

Stem Cell
Stem cells are unspecialized cells with the ability to develop into many other types of cells in the body. Learn about the role they play in bone marrow.

Stem Cell Transplant
Stem cell or marrow transplantation helps to restore normal blood production after high dose therapy for cancer. Learn more about this type of therapy.

Syngeneic
Find out the meaning of the term syngeneic and the advantages and disadvantages to this type of stem cell transplant.

T-cells
A T-cell is a type of blood cell that protects the body from infection. Find out more about T-cells.

T Lymphocyte
Learn about how T lymphocytes help fight infection.

Thrombocytopenia
Thrombocytopenia suggests low counts of platelets. Understand thrombocytopenia better.

Thrombocytopenia
Learn what thrombocytopenia is and how it affects the body.

What is a Tunneled Central Line (CVC)
A definition of a tunneled central line (CVC)

Tonsils
Learn how to locate your tonsils, and about the role they play in fighting infection.

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