R-CHOP is the abbreviated name of a cobination of drugs used in chemotherapy for aggressive Non-Hodgkin Lymphomas (NHL). It is a relatively new combination which adds the drug Rituximab - a monoclonal antibody, to the standard combination called CHOP. CHOP consists of four chemotherapy drugs (see the page on CHOP).
Rituximab is administered as an infusion over a few hours on the first day of treatment, while the drugs of the CHOP regimen may be started the next day. The entire course is usually repeated every three weeks for 6-8 cycles.
R-CHOP is now considered a standard chemotherapy regimen for Diffuse Large B-Cell Lymphoma (BLBCL), the commonest type of Non-Hodgkin Lymphoma.